The emergence of novel cell therapy technologies has led to questions about the necessity of human leukocyte antigen matching (HLA matching) in the development of potential “universal” allogeneic cell therapies. After all, if you can eliminate alloreactive responses, what role would HLA matching play? Martin Maiers, MS, is the Vice President of Biomedical Informatics for…
This is no doubt an exciting time in the cell and gene therapy field. Hundreds of cell and gene therapy products are currently in clinical trials. And earlier this year, former FDA Commissioner Scott Gottlieb, MD, and Peter Marks, MD, PhD, director, Center for Biologics Evaluation and Research, predicted the FDA will approve 10 to…
CAR-T therapies progressed to market at an unprecedented pace. Due to their accelerated FDA approvals, long-term data on how patients fare post-treatment isn’t readily available. As the number of patients commercially treated with CAR-T therapy grows, long-term outcomes data has the potential to influence the entire industry of personalized cell and gene therapies. As with…